Gw9508 cayman chemical
WebNov 23, 2024 · Product name : GW9508 Product Number : G9797 Brand : Sigma CAS-No. : 885101-89-3 1.2 Relevant identified uses of the substance or mixture and uses advised against ... To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. SECTION 12: Ecological information 12.1 … WebGW 9508 is a potent and selective agonist for the free fatty acid receptor FFA1 (GPR40) (pEC 50 values are 7.32, < 4.3 and < 4.3 for FFA1, FFA2 and FFA3 receptors respectively). Inactive against a range of other GPCRs, kinases, proteases, integrins and PPARs. Potentiates glucose-stimulated insulin secretion in MIN6 cells (pEC 50 = 6.14).
Gw9508 cayman chemical
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WebGW9508 (4-(3-Phenoxybenzylamino)phenylpropionic acid);≥98% HPLC; This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC 1280), a biologically annotated collection of high-quality, ready-to-screen compounds; GW9508 is a selective FFA WebGW 9508 is a small-molecule agonist of GPR40/FFA1 (EC 50 = 47.8 nM for calcium mobilization in HEK293 cells). 1 It is selective for GPR40/FFA1 over GPR120/FFA4 (EC …
WebJan 18, 2024 · Use of GW9508 GW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32, 100-fold selective against GPR120, stimulates insulin secretion in a glucose-sensitive manner.IC50 value: 7.32 (pEC50) [1]Target: GPR40GW9508 is shown to be at least 100-fold selective against 220 other GPCRs, 60 kinases, 63 proteases, seven … WebGW9508 is shown to be at least 100-fold selective against 220 other GPCRs, 60 kinases, 63 proteases, seven integrins and 20 nuclear receptors including PPARα, δ and γ (pEC50 4.0, 4 and 4.9, respectively). ... Enter the chemical formula of a compound to calculate its molar mass and elemental composition: Calculate. Total Molecular Weight: g ...
WebJan 1, 2015 · GW9508 (Cayman Chemical Company, Ann Arbor, MI) and LA (MP Biomedicals, Santa Ana, CA), which are agonists for both GPR40 and GPR120, and GW1100 (Haoyuan Chemexpress Co, Ltd, Shanghai, China), a specific antagonist for GPR40, 33 were used to evaluate the involvement of GPRs in GLP-2 production. … WebGW9508 ≥98% (HPLC); CAS Number: 885101-89-3; Synonyms: 4-(3-フェノキシベンジルアミノ)フェニルプロピオン酸; find Sigma-Aldrich-G9797 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich
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WebNov 15, 2013 · As described above, cells were first serum starved and then incubated for 24 h in the presence of vehicule (DMSO) or 1–100 µM of GW9508 (Cayman … cargo ship functionWebGW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 … brother innov-is nv 1800qWebFeb 26, 2024 · Third, GW9508, an agonist of free fatty acid receptor 1 (FFAR1) and FFAR4, prevented the increase in SOX9 induced by serum deprivation or LRS in the three cell … brother innov-is nv180WebApr 24, 2014 · agonist GW9508 (Cayman Chemical Co., Ann Arbor, MI, USA) was dissolved in 4% dimethyl sulfoxide ... However, using members of two chemical series … cargo ship galleyWebGW 9508 is a potent and selective agonist for the free fatty acid receptor FFA1 (GPR40) (pEC 50 values are 7.32, < 4.3 and < 4.3 for FFA1, FFA2 and FFA3 receptors … cargo ship funnelWebGW9508 (4-(3-Phenoxybenzylamino)phenylpropionic acid);≥98% HPLC; This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC … cargo ship full of porschesWebGW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 has anti-inflammatory and anti-atherosclerotic activities. ... brother innovis nv15